Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders

O5: Stigma in Psychiatric Disorders

Social stigma is a major challenge among the patients with mental illness, their families and the health care providers. Not only the patient with psychological disorders, but also who has an infectious disease suffer social stigma. Stigma refers to an extreme and unusual disapproval of a person from the other members of society. Stigma is a Greek word that in its origins referred to a type of ...

Virus infection as a cause of inflammation in psychiatric disorders.

Many neurotropic viruses exist and may cause classical inflammation but also low-level neuroinflammation. However, viruses may be dormant within the CNS and become active later. The role of neurotropic virus infections in the causation of psychiatric disorders may be underestimated, because the diagnostic approach to the CNS is difficult and to dormant infections in general, but especially with...

Psychiatric disorders and behavioral functions in offsprings of bipolar parents

Introduction: Psychiatric disorders and function of child and adolescent offsprings of bipolar parents were compared to that of their peers with healthy parents. Methods: In this case - control study, 52 bipolar parents along with their 72 children were compared with 48 healthy and their 63 children. The subjects were selected by simple and available methods. K-SADS, C-GAS were to collect...

Eicosanoids Derived From Arachidonic Acid and Their Family Prostaglandins and Cyclooxygenase in Psychiatric Disorders

Arachidonic acid (AA)-derived lipid mediators are called eicosanoids. Eicosanoids have emerged as key regulators of a wide variety of physiological responses and pathological processes, and control important cellular processes. AA can be converted into biologically active compounds by metabolism by cyclooxygenases (COX). Beneficial effect of COX-2 inhibitor celecoxib add-on therapy has been rep...

Efficacy and Safety of Rituximab in patients with Neuromyelitis Optica Spectrum Disorders: A prospective observation in Iranian Cases.